RGS proteins, widely known to negatively regulate G-protein signalling have postive regulatory effect as well. Smith et al., (2009) demostrates this dual nature of RGS proteins using mathematical models and in vivo experiments.
BioModels now provides 1516 literature-based models.
Live now - an interactive map of molecular processes described by mechanistic models of neurodegenerative diseases.
We are extremely happy to announce the 30th release of BioModels, which now provides access to 1483 literature-based models and 143,070 models automatically generated from pathway resources, with additional and updated features.
The proposal we submitted to BBSRC (BBR fund) for the development of BioModels towards multi-scale modelling succeeded. It is a joint proposal between EMBL-EBI and Babraham Institute.