Short description

This a model from the article:
Calcium spiking.
Meyer T, Stryer L Annu Rev Biophys Biophys Chem1991:20:153-74 1867714,
Abstract:
No Abstract Available

The IP3-Ca2+ Crosscoupling Model (ICC) is reviewed by Meyer and Stryer in 1991, originally from Meyer and Stryer, 1988. PMID - 2455890 Parameters refer to figures 5 and 6 of the article which were reproduced by using Copasi 4.5 (Build 30). Species CaI and IP3 are buffered to 1% and 50% percent, respectively.

This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2009 The BioModels Team.
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To cite BioModels Database, please use Le Novère N., Bornstein B., Broicher A., Courtot M., Donizelli M., Dharuri H., Li L., Sauro H., Schilstra M., Shapiro B., Snoep J.L., Hucka M. (2006) BioModels Database: A Free, Centralized Database of Curated, Published, Quantitative Kinetic Models of Biochemical and Cellular Systems Nucleic Acids Res., 34: D689-D691.

Format
SBML (L2V4)
Related Publication
  • Calcium spiking.
  • Meyer T, Stryer L.
  • Annu Rev Biophys Biophys Chem 1991; 20: 153-174 , 0/ 1991 , Volume 20 , pages: 153-174
  • Department of Cell Biology, Sherman Fairchild Center, Stanford University School of Medicine, California 94305.
Contributors
Philipp Bayer

Metadata information

is
BioModels Database MODEL9412103933
BioModels Database BIOMD0000000224
isDescribedBy
PubMed 1867714
isDerivedFrom
PubMed 2455890
hasTaxon
Taxonomy Rattus rattus
Curation status
Curated
  • Model originally submitted by : Philipp Bayer
  • Submitted: Aug 4, 2009 8:55:09 PM
  • Last Modified: May 28, 2014 1:43:04 AM
Revisions
  • Version: 2 public model Download this version
    • Submitted on: May 28, 2014 1:43:04 AM
    • Submitted by: Philipp Bayer
    • With comment: Current version of Meyer1991_CalciumSpike_ICC
  • Version: 1 public model Download this version
    • Submitted on: Aug 4, 2009 8:55:09 PM
    • Submitted by: Philipp Bayer
    • With comment: Original import of meyer1991_ICC_buffered
Curator's comment:
(added: 05 Aug 2009, 15:12:36, updated: 05 Aug 2009, 15:12:36)
Figure 6 of the reference publication is reproduced. The model was integrated and simulated using Copasi v4.5 (Build 30).