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Base excision repair - Rhodospirillum centenum (strain ATCC 51521 / SW)

 

Model information
Identifier: BMID000000009814
Format: SBML L3 V1 (Layout, Qualitative Models)
Project: path2models
Categories: non-metabolic
Submission: 17 May 2012 16:31:51 UTC
Last modified: 08 Dec 2012 01:30:50 UTC
Published: 20 May 2012 00:49:21 UTC
Annotations
isDescribedBy base-excision repair, DNA ligation Gene Ontology
isDescribedBy base-excision repair, gap-filling Gene Ontology
isDescribedBy base-excision repair, base-free sugar-phosphate removal Gene Ontology
isDescribedBy base-excision repair, AP site formation Gene Ontology
isDescribedBy base-excision repair Gene Ontology
occursIn Rhodospirillum centenum (strain ATCC 51521 / SW) Taxonomy
isDerivedFrom Base excision repair KEGG Pathway
Notes
Model of “Base excision repair” in “Rhodospirillum centenum SW”
Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub-pathways: short-patch BER where only one nucleotide is replaced and long-patch BER where 2-13 nucleotides are replaced. Each sub-pathway of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a coordinated fashion. This process of complex formation appears to provide an increase in specificity and efficiency to the BER pathway, thereby facilitating the maintenance of genome integrity by preventing the accumulation of highly toxic repair intermediates.

Graphical representation of 'Base excision repair (Rhodospirillum centenum SW)'
(PNG image hosted by the Kyoto Encyclopedia of Genes and Genomes, KEGG).
This model has been automatically generated by KEGGtranslator V2.3.0 (KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats. Wrzodek C, Dräger A, Zell A. Bioinformatics . 2011, 27 :2314-2315) using information coming from the KEGG PATHWAY Database ( original pathway ).
This model has been produced by the path2models project, it is currently hosted on BioModels Database and identified by: BMID000000009814 .
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.
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