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ABC transporters - Anaerocellum thermophilum (strain DSM 6725 / Z-1320)


Model information
Identifier: BMID000000014074
Format: SBML L3 V1 (Layout, Qualitative Models)
Project: path2models
Categories: non-metabolic
Submission: 17 May 2012 17:14:32 UTC
Last modified: 07 Dec 2012 20:56:29 UTC
Published: 20 May 2012 00:49:21 UTC
isDescribedBy ATP-binding cassette (ABC) transporter complex Gene Ontology
isDescribedBy ATP-binding cassette (ABC) transporter complex Gene Ontology
isDescribedBy ATP-binding cassette (ABC) transporter complex Gene Ontology
occursIn Anaerocellum thermophilum (strain DSM 6725 / Z-1320) Taxonomy
isDerivedFrom ABC transporters KEGG Pathway
Model of “ABC transporters” in “Caldicellulosiruptor bescii DSM 6725”
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).

Graphical representation of 'ABC transporters (Caldicellulosiruptor bescii DSM 6725)'
(PNG image hosted by the Kyoto Encyclopedia of Genes and Genomes, KEGG).
This model has been automatically generated by KEGGtranslator V2.3.0 (KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats. Wrzodek C, Dräger A, Zell A. Bioinformatics . 2011, 27 :2314-2315) using information coming from the KEGG PATHWAY Database ( original pathway ).
This model has been produced by the path2models project, it is currently hosted on BioModels Database and identified by: BMID000000014074 .
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.