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Two-component system - Coxiella burnetii (strain RSA 331 / Henzerling II)


Model information
Identifier: BMID000000015767
Format: SBML L3 V1 (Layout, Qualitative Models)
Project: path2models
Categories: non-metabolic
Submission: 17 May 2012 17:34:22 UTC
Last modified: 07 Dec 2012 21:46:13 UTC
Published: 20 May 2012 00:49:21 UTC
isDescribedBy two-component signal transduction system (phosphorelay) Gene Ontology
occursIn Coxiella burnetii (strain RSA 331 / Henzerling II) Taxonomy
isDerivedFrom Two-component system KEGG Pathway
Model of “Two-component system” in “Coxiella burnetii RSA 331”
Two-component signal transduction systems enable bacteria to sense, respond, and adapt to changes in their environment or in their intracellular state. Each two-component system consists of a sensor protein-histidine kinase (HK) and a response regulator (RR). In the prototypical two-component pathway, the sensor HK phosphorylates its own conserved His residue in response to a signal(s) in the environment. Subsequently, the phosphoryl group of HK is transferred onto a specific Asp residue on the RR. The activated RR can then effect changes in cellular physiology, often by regulating gene expression. Two-component pathways thus often enable cells to sense and respond to stimuli by inducing changes in transcription.

Graphical representation of 'Two-component system (Coxiella burnetii RSA 331)'
(PNG image hosted by the Kyoto Encyclopedia of Genes and Genomes, KEGG).
This model has been automatically generated by KEGGtranslator V2.3.0 (KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats. Wrzodek C, Dräger A, Zell A. Bioinformatics . 2011, 27 :2314-2315) using information coming from the KEGG PATHWAY Database ( original pathway ).
This model has been produced by the path2models project, it is currently hosted on BioModels Database and identified by: BMID000000015767 .
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.