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Peptidoglycan biosynthesis - Anaerocellum thermophilum (strain DSM 6725 / Z-1320)

 

Model information
Identifier: BMID000000085986
Format: SBML L3 V1 (Layout)
Project: path2models
Categories: metabolic
Submission: 18 May 2012 12:00:06 UTC
Last modified: 09 Dec 2012 16:30:19 UTC
Published: 20 May 2012 00:49:21 UTC
Annotations
occursIn Anaerocellum thermophilum (strain DSM 6725 / Z-1320) Taxonomy
isDerivedFrom Peptidoglycan biosynthesis KEGG Pathway
Notes
Model of “Peptidoglycan biosynthesis” in “Caldicellulosiruptor bescii DSM 6725”
Peptidoglycan is a macromolecule made of long aminosugar strands cross-linked by short peptides. It forms the cell wall in bacteria surrounding the cytoplasmic membrane. The glycan strands are typically comprised of repeating N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc) disaccharides. Each MurNAc is linked to a peptide of three to five amino acid residues. Disaccharide subunits are first assembled on the cytoplasmic side of the bacterial membrane on a polyisoprenoid anchor (lipid I and II). Polymerization of disaccharide subunits by transglycosylases and cross-linking of glycan strands by transpeptidases occur on the other side of the membrane. Bacterial cell wall biosynthesis inhibitors form a major class of antibiotics.

Graphical representation of 'Peptidoglycan biosynthesis (Caldicellulosiruptor bescii DSM 6725)'
(PNG image hosted by the Kyoto Encyclopedia of Genes and Genomes, KEGG).
This model has been automatically generated by KEGGtranslator V2.2.0 (KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats. Wrzodek C, Dräger A, Zell A. Bioinformatics . 2011, 27 :2314-2315) using information coming from the KEGG PATHWAY Database ( original pathway ).
The missing kinetic equations were added by SBMLsqueezer .
This model has been produced by the path2models project, it is currently hosted on BioModels Database and identified by: BMID000000085986 .
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.
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