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Citrate cycle (TCA cycle) - Shigella flexneri serotype 5b (strain 8401)

 

Model information
Identifier: BMID000000087157
Format: SBML L3 V1 (Layout)
Project: path2models
Categories: metabolic
Submission: 18 May 2012 12:19:42 UTC
Last modified: 10 Dec 2012 09:41:03 UTC
Published: 20 May 2012 00:49:21 UTC
Annotations
isDescribedBy tricarboxylic acid cycle Gene Ontology
occursIn Shigella flexneri serotype 5b (strain 8401) Taxonomy
isDerivedFrom Citrate cycle (TCA cycle) KEGG Pathway
Notes
Model of “Citrate cycle (TCA cycle)” in “Shigella flexneri 8401 (serotype 5b)”
The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011].

Graphical representation of 'Citrate cycle (TCA cycle) (Shigella flexneri 8401 (serotype 5b))'
(PNG image hosted by the Kyoto Encyclopedia of Genes and Genomes, KEGG).
This model has been automatically generated by KEGGtranslator V2.2.0 (KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats. Wrzodek C, Dräger A, Zell A. Bioinformatics . 2011, 27 :2314-2315) using information coming from the KEGG PATHWAY Database ( original pathway ).
The missing kinetic equations were added by SBMLsqueezer .
This model has been produced by the path2models project, it is currently hosted on BioModels Database and identified by: BMID000000087157 .
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.
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