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Other types of O-glycan biosynthesis - Pongo abelii


Model information
Identifier: BMID000000095902
Format: SBML L3 V1 (Layout)
Project: path2models
Categories: metabolic
Submission: 18 May 2012 14:43:01 UTC
Last modified: 10 Dec 2012 06:56:13 UTC
Published: 20 May 2012 00:49:21 UTC
occursIn Pongo abelii Taxonomy
isDerivedFrom Other types of O-glycan biosynthesis KEGG Pathway
Model of “Other types of O-glycan biosynthesis” in “Pongo abelii (Sumatran orangutan)”
O-mannosyl glycans are a type of O-glycans that are found both in eukaryotes and prokaryotes. Biosynthesis of O-mannosyl glycans is initiated by the transfer of mannose from Man-P-Dol to serine or threonine residue, which is catalyzed by protein O-mannosyltransferases POMT1 and POMT2. Defects of these genes are linked to human diseases, such as muscular dystrophies caused by reduced O-mannosylation of alpha-dystroglycan in skeletal muscles [DS:H00120].

Graphical representation of 'Other types of O-glycan biosynthesis (Pongo abelii (Sumatran orangutan))'
(PNG image hosted by the Kyoto Encyclopedia of Genes and Genomes, KEGG).
This model has been automatically generated by KEGGtranslator V2.2.0 (KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats. Wrzodek C, Dräger A, Zell A. Bioinformatics . 2011, 27 :2314-2315) using information coming from the KEGG PATHWAY Database ( original pathway ).
The missing kinetic equations were added by SBMLsqueezer .
This model has been produced by the path2models project, it is currently hosted on BioModels Database and identified by: BMID000000095902 .
To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.