Lenbury1991_CortisolSecretionSystem

  public model
Short description

This a model from the article:
Modelling fluctuation phenomena in the plasma cortisol secretion system in normal man.
Lenbury Y, Pacheenburawana P. Biosystems. 1991;26(2):117-25. 1668715 ,
Abstract:
A system of three non-linear differential equations with exponential feedback terms is proposed to model the self-regulating cortisol secretion system and explain the fluctuation patterns observed in clinical data. It is shown that the model exhibits bifurcation and chaos patterns for a certain range of parametric values. This helps us to explain clinical observations and characterize different dynamic behaviors of the self-regulative system.

This model was taken from the CellML repository and automatically converted to SBML.
The original model was: Lenbury Y, Pacheenburawana P. (1991) - version02
The original CellML model was created by:
Lloyd, Catherine, May
c.lloyd@aukland.ac.nz
The University of Auckland
The Bioengineering Institute

This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team.
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To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.

Format
SBML (L2V3)
Related Publication
  • Modelling fluctuation phenomena in the plasma cortisol secretion system in normal man.
  • Lenbury Y, Pacheenburawana P
  • Bio Systems , 0/ 1991 , Volume 26 , pages: 117-125
  • Department of Mathematics, Faculty of Science, Mahidol University, Bangkok, Thailand.
  • A system of three non-linear differential equations with exponential feedback terms is proposed to model the self-regulating cortisol secretion system and explain the fluctuation patterns observed in clinical data. It is shown that the model exhibits bifurcation and chaos patterns for a certain range of parametric values. This helps us to explain clinical observations and characterize different dynamic behaviors of the self-regulative system.
Contributors
Vijayalakshmi Chelliah

Metadata information

is
BioModels Database MODEL0479926177
isDescribedBy
PubMed 1668715
hasTaxon
Taxonomy Homo sapiens
isVersionOf
Gene Ontology cortisol secretion
hasProperty
Mathematical Modelling Ontology Ordinary differential equation model
Curation status
Non-curated
Original model(s)
http://www.cellml.org/models/lenbury_pacheenburawana_1991_version02
Name Description Size Actions

Model files

MODEL0479926177_url.xml SBML L2V3 representation of Lenbury1991_CortisolSecretionSystem 8.42 KB Preview | Download

Additional files

MODEL0479926177.vcml Auto-generated VCML file 900.00 bytes Preview | Download
MODEL0479926177-biopax3.owl Auto-generated BioPAX (Level 3) 2.00 KB Preview | Download
MODEL0479926177.svg Auto-generated Reaction graph (SVG) 851.00 bytes Preview | Download
MODEL0479926177.png Auto-generated Reaction graph (PNG) 5.04 KB Preview | Download
MODEL0479926177.pdf Auto-generated PDF file 126.68 KB Preview | Download
MODEL0479926177.sci Auto-generated Scilab file 156.00 bytes Preview | Download
MODEL0479926177.xpp Auto-generated XPP file 1.43 KB Preview | Download
MODEL0479926177-biopax2.owl Auto-generated BioPAX (Level 2) 1.05 KB Preview | Download
MODEL0479926177_urn.xml Auto-generated SBML file with URNs 8.96 KB Preview | Download
MODEL0479926177.m Auto-generated Octave file 2.48 KB Preview | Download

  • Model originally submitted by : Vijayalakshmi Chelliah
  • Submitted: Apr 28, 2009 12:54:17 PM
  • Last Modified: Apr 28, 2009 12:54:17 PM
Revisions
  • Version: 2 public model Download this version
    • Submitted on: Apr 28, 2009 12:54:17 PM
    • Submitted by: Vijayalakshmi Chelliah
    • With comment: Current version of Lenbury1991_CortisolSecretionSystem
  • Version: 1 public model Download this version
    • Submitted on: Apr 28, 2009 12:54:17 PM
    • Submitted by: Vijayalakshmi Chelliah
    • With comment: Original import of Lenbury1991_CrotisolSecretionSystem