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MODEL0479926177 - Lenbury1991_CortisolSecretionSystem


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Reference Publication
Publication ID: 1668715
Lenbury Y, Pacheenburawana P.
Modelling fluctuation phenomena in the plasma cortisol secretion system in normal man.
BioSystems 1991; 26(2): 117-125
Department of Mathematics, Faculty of Science, Mahidol University, Bangkok, Thailand.  [more]
Original Model: CellML logo
Submitter: Vijayalakshmi Chelliah
Submission Date: 28 Apr 2009 12:54:17 UTC
Last Modification Date: 28 Apr 2009 12:54:17 UTC
Creation Date: 28 Apr 2009 12:54:17 UTC
bqbiol:isVersionOf Gene Ontology cortisol secretion
bqbiol:hasTaxon Taxonomy Homo sapiens

This a model from the article:
Modelling fluctuation phenomena in the plasma cortisol secretion system in normal man.
Lenbury Y, Pacheenburawana P. Biosystems. 1991;26(2):117-25. 1668715 ,
A system of three non-linear differential equations with exponential feedback terms is proposed to model the self-regulating cortisol secretion system and explain the fluctuation patterns observed in clinical data. It is shown that the model exhibits bifurcation and chaos patterns for a certain range of parametric values. This helps us to explain clinical observations and characterize different dynamic behaviors of the self-regulative system.

This model was taken from the CellML repository and automatically converted to SBML.
The original model was: Lenbury Y, Pacheenburawana P. (1991) - version02
The original CellML model was created by:
Lloyd, Catherine, May
The University of Auckland
The Bioengineering Institute

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