Smallbone2013 - Human metabolism global reconstruction (recon 2.1x)

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Short description
Smallbone2013 - Human metabolism global reconstruction (recon 2.1x)

Recon 2.1x.

This model is described in the article:

Kieran Smallbone
Molecular Networks (q-bio.MN)

Abstract:

Recon 2 is a highly curated reconstruction of the human metabolic network. Whilst the network is state of the art, it has shortcomings, including the presence of unbalanced reactions involving generic metabolites. By replacing these generic molecules with each of their specific instances, we can ensure full elemental balancing, in turn allowing constraint-based analyses to be performed. The resultant model, called Recon 2.1, is an order of magnitude larger than the original.

To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.

Format
SBML (L2V4)
Related Publication
  • Striking a balance with Recon 2.1
  • Kieran Smallbone
  • Molecular Networks (q-bio.MN) 2013
  • University of Manchester
  • Recon 2 is a highly curated reconstruction of the human metabolic network. Whilst the network is state of the art, it has shortcomings, including the presence of unbalanced reactions involving generic metabolites. By replacing these generic molecules with each of their specific instances, we can ensure full elemental balancing, in turn allowing constraint-based analyses to be performed. The resultant model, called Recon 2.1, is an order of magnitude larger than the original.
Contributors
Kieran Smallbone

Metadata information

is
BioModels Database MODEL1311110001
occursIn
Taxonomy Homo sapiens
isVersionOf
isDescribedBy
arXiv 1311.5696
Curation status
Non-curated
  • Model originally submitted by : Kieran Smallbone
  • Submitted: Nov 11, 2013 12:58:24 PM
  • Last Modified: Nov 26, 2013 11:43:59 AM
Revisions
  • Version: 2 public model Download this version
    • Submitted on: Nov 26, 2013 11:43:59 AM
    • Submitted by: Kieran Smallbone
    • With comment: Current version of Smallbone2013 - Human metabolism global reconstruction (recon 2.1x)
  • Version: 1 public model Download this version
    • Submitted on: Nov 11, 2013 12:58:24 PM
    • Submitted by: Kieran Smallbone
    • With comment: Original import of recon 2.1